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Using deletional promoter contructs (ff-luc) of human IL-16 promoter from ca. -3.3kb to +200, we found constitutive high levels of transcriptional activation in transfected Jurkat cells in constructs from -3.3kb to -1,000bp, consistent with the known...

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Biochemistry of Respiratory Disease, Astra Zeneca, Loughborough, UK 2009: Asthmatic airway remodelling is characterized by an increase number and size of submucosal vessels. Although a consistent and long recognized pathologic finding, the...

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Idiopathic pulmonary arterial hypertension (IPAH) is associated with lower levels of the pulmonary vasodilator nitric oxide (NO) and its biochemical reaction products (NO2-, NO3-) in part due to reduction of pulmonary endothelial NO synthesis. However...

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